Products for Research Use Only

NEDD4 (M) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210296Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210296Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to NEDD4.Neural precursor cell expressed developmentally down-regulated protein 4 (NEDD4) is an E3ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form ofa thioester and then directly transfers the ubiquitin to targeted substrates. NEDD4 is also involved inthe pathway leading to the degradation of VEGFR-2/KDFR independent of its ubiquitin-ligase activity.NEDD4 can monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization anddegradation in lysosomes. In addition, NEDD4 is part of a signaling complex composed of NEDD4, RAP2A and TNIK, which regulates neuronal dendrite extension and arborization during development.
Product Name Alternative
Anti-NEDD4 antibody, anti-E3 ubiquitinprotein ligase NEDD4 antibody, anti-Cell proliferationinducing gene 53 protein antibody, anti-Neural precursor cell expressed developmentally downregulated protein 4 antibody, anti-NEDD4 antibody, anti-KIAA0093 antibody, anti-NEDD41 antibody
UniProt
P46934
Reactivity
Human, Mouse
Immunogen
Middle region of human NEDD4
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Neuroscience
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
149
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3