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GSK3A (C) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210023Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210023Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to GSK3A.Glycogen synthase kinase 3 (GSK-3), a serine-threonine kinase with two isoforms (alpha and beta), was originally discovered as a key enzyme in glycogen metabolism. GSK-3 was subsequently shownto function in cell division, proliferation, motility and survival. Glycogen synthase kinase 3-alpha (GSK3A) is a multifunctional protein serine kinase, homologous to Drosophila 'shaggy' (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synthase andtranscription factors. It also plays a role in the WNT and PI3K signaling pathways.
Product Name Alternative
Anti-GSK3A antibody, anti-Glycogen synthase kinase3 alpha antibody, anti-GSK3 alpha antibody
UniProt
P49840
Reactivity
Human, Mouse
Immunogen
C-terminal region of human GSK3A
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
51
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · P49840

Glycogen synthase kinase-3 alpha

GSK3A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P49840
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GSK3A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GSK-3 alpha
EC number
2.7.11.26
Processing
—
Secondary accessions
O14959
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Disease

Alzheimer diseaseDiabetes mellitus

Ligand

ATP-bindingNucleotide-binding

Biological process

Carbohydrate metabolismGlycogen metabolismNeurogenesisWnt signaling pathway

Molecular function

KinaseSerine/threonine-protein kinaseSignal transduction inhibitorTransferase

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