Recombinant UBE2G2 Protein

• Short Description:

  Catalog Number: B2017710 (50 µg)_x000D_ Recombinant UBE2G2 protein is a version of the UBE2G2 protein that is produced using recombinant DNA technology. UBE2G2 is an enzyme that plays a role in the ubiquitination process, which is a key mechanism for regulating protein degradation and other cellular processes. Recombinant UBE2G2 protein can be used in research studies to investigate its function and interactions with other proteins. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Description:

  Recombinant UBE2G2 Protein_x000D_ Catalog number: B2017710_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 20.73 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Ubiquitin conjugating enzyme E2 G2, UBC7_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Li W, Tu D, Brunger AT, Ye Y. A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate Nature. 2007 Mar 15;446(7133):333-7._x000D_ 2: Liu W, Shang Y, Li W. gp78 elongates of polyubiquitin chains from the distal end through the cooperation of its G2BR and CUE domains Sci Rep. 2014 Nov 20;4:7138._x000D_ 3: Reyes LF, Sommer CA, Beltramini LM, Henrique-Silva F. Expression, purification, and structural analysis of (HIS)UBE2G2 (human ubiquitin-conjugating enzyme) Protein Expr Purif. 2006 Feb;45(2):324-8._x000D_ 4: Lv Z, Rickman KA, Yuan L, Williams K, Selvam SP, Woosley AN, Howe PH, Ogretmen B, Smogorzewska A, Olsen SK. S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity Mol Cell. 2017 Feb 16;65(4):699-714.e6._x000D_ 5: Flierman D, Coleman CS, Pickart CM, Rapoport TA, Chau V. E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11589-94._x000D_ 6: Marteijn JA, van der Meer LT, Smit JJ, Noordermeer SM, Wissink W, Jansen P, Swarts HG, Hibbert RG, de Witte T, Sixma TK, Jansen JH, van der Reijden BA. The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains Leukemia. 2009 Aug;23(8):1480-9._x000D_ 7: Bernardi KM, Williams JM, Kikkert M, van Voorden S, Wiertz EJ, Ye Y, Tsai B. The E3 ubiquitin ligases Hrd1 and gp78 bind to and promote cholera toxin retro-translocation Mol Biol Cell. 2010 Jan 1;21(1):140-51._x000D_ 8: Li F, Wang L, Burgess RJ, Weinshilboum RM. Thiopurine S-methyltransferase pharmacogenetics: autophagy as a mechanism for variant allozyme degradation Pharmacogenet Genomics. 2008 Dec;18(12):1083-94._x000D_ 9: Kikkert M, Doolman R, Dai M, Avner R, Hassink G, van Voorden S, Thanedar S, Roitelman J, Chau V, Wiertz E. Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum J Biol Chem. 2004 Jan 30;279(5):3525-34._x000D_ 10: Ambivero CT, Cilenti L, Main S, Zervos AS. Mulan E3 ubiquitin ligase interacts with multiple E2 conjugating enzymes and participates in mitophagy by recruiting GABARAP Cell Signal. 2014 Dec;26(12):2921-9. _x000D_ _x000D_ Products Related to Recombinant UBE2G2 Protein can be found at Proteins

• CAS Number:

  9000-83-3

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5