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Enterostatin (human, mouse, rat)

CAT: 0804-HY-P1067-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1067-01Size:5 mg
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Description
Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.
CAS Number
117830-79-2
UNSPSC
12352209
Target
Endogenous Metabolite
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Enterostatin,_human,_mouse,_rat.html
Purity
99.33
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
N=C(N)NCCC[C@@H](C(O)=O)NC([C@H]1N(CCC1)C(CNC([C@H]2N(CCC2)C([C@@H](N)C)=O)=O)=O)=O
Molecular Formula
C21H36N8O6
Molecular Weight
496.56
References & Citations
[1]Silvestre RA, et al. Effect of enterostatin on insulin, glucagon, and somatostatin secretion in the perfused rat pancreas. Diabetes. 1996 Sep;45 (9) :1157-60.|[2]Erlanson-Albertsson C, et al. Enterostatin--a peptide regulating fat intake. Obes Res. 1997 Jul;5 (4) :360-72.|[3]Ohinata K, et al. Enterostatin (APGPR) enhances memory consolidation in mice. Peptides. 2007 Mar;28 (3) :719-21.|[4]Sörhede M, et al. Enterostatin: a gut-brain peptide regulating fat intake in rat. J Physiol Paris. 1993;87 (4) :273-5.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

Chemical Information

Enterostatin

APGPR Enterostatin is a peptide.

CAS Number117830-79-2
PubChem CID3082883
IUPAC Name(2S)-2-[[(2S)-1-[2-[[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Molecular FormulaC21H36N8O6
Molecular Weight496.6
XLogP-5
Topological Polar Surface Area227
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count8
Rotatable Bond Count11
Heavy Atom Count35
Formal Charge0
Complexity846
SMILES
C[C@@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)N
InChI
InChI=1S/C21H36N8O6/c1-12(22)19(33)29-10-4-6-14(29)17(31)26-11-16(30)28-9-3-7-15(28)18(32)27-13(20(34)35)5-2-8-25-21(23)24/h12-15H,2-11,22H2,1H3,(H,26,31)(H,27,32)(H,34,35)(H4,23,24,25)/t12-,13-,14-,15-/m0/s1
InChIKey
ITZMJCSORYKOSI-AJNGGQMLSA-N
Chemical Structure
2D Structure
2D structure of Enterostatin
CAS: 117830-79-2
CID: 3082883
Formula: C21H36N8O6
MW: 496.6
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight496.6
XLogP3-5
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count8
Rotatable Bond Count11
Exact Mass496.27578090
Monoisotopic Mass496.27578090
Topological Polar Surface Area227 Ų
Heavy Atom Count35
Formal Charge0
Complexity846
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes