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DiAzKs

CAT: 0804-HY-D0853-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-D0853-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DiAzKs (H-L-Photo-lysine) is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs acts as a UV light-activated photo-crosslinking probe[1][2][3].
CAS Number
1253643-88-7
Product Name Alternative
H-L-Photo-lysine
UNSPSC
12171500
Hazard Statement
H242
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/diazks.html
Purity
99.93
Solubility
DMSO : 2 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic)
Smiles
N[C@@H](CCCCNC(OCCC1(C)N=N1)=O)C(O)=O
Molecular Formula
C11H20N4O4
Molecular Weight
272.30
Precautions
H242
References & Citations
[1]Ai HW, et al. Probing protein-protein interactions with a genetically encoded photo-crosslinking amino acid. Chembiochem. 2011 Aug 16;12 (12) :1854-7.|[2]Chatterjee A, et al. Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells. Proc Natl Acad Sci U S A. 2013 Jul 16;110 (29) :11803-8.|[3]Yang T, et al. Photo-lysine captures proteins that bind lysine post-translational modifications. Nat Chem Biol. 2016 Feb;12 (2) :70-2.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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