7-Ethoxyresorufin-d5

7-Ethoxyresorufin-d5

• CAS Number: 2749329-28-8
• UNSPSC Description: 7-Ethoxyresorufin-d5 is deuterium labeled 7-Ethoxyresorufin. 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2].
• Target Antigen: Cytochrome P450; Isotope-Labeled Compounds; NO Synthase
• Type: Isotope-Labeled Compounds
• Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease;Others
• Field of Research: Others
• Solubility: 10 mM in DMSO
• Smiles: O=C1C=C2OC3=CC(OC([2H])([2H])C([2H])([2H])[2H])=CC=C3N=C2C=C1
• Molecular Weight: 246.27
• References & Citations: [1]C G Li, et al. Inhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450. Br J Pharmacol. 1996 May;118(1):57-62.|[2]Thomas K H Chang, et al. Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. Methods Mol Biol. 2006;320:85-90.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported