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CLEC4E Antibody

CAT: 0013-GTR18206866-01Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18206866-01Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse Monoclonal antibody to CLEC4E.CLEC4E (MINCLE or CLECSF9), belongs to a diverse family of proteins which were originally defined by their ability to recognize a wide range of ligands of carbohydrate structure. MINCLE is expressed in macrophages subjected to several types of stress. CLEC4E has an important role in response to trehalose-6,6-dimycolate (TDM) and activated by a synthetic analogue, trehalose dibehenate (TDB) . It was reported recently that MINCLE is connected with an immunoreceptor tyrosine-based activation motif-containing Fc receptor chain (FcR) and functions as an activating receptor for damaged self- and non-self-pathogenic fungi.
Product Name Alternative
C-type lectin domain family 4 member E, C-type lectin superfamily member 9, Macrophage-inducible C-type lectin, CLEC4E, CLECSF9, MINCLE.
Immunogen
Anti-human CLEC4E mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CLEC4E amino acids 41-219 purified from E. coli
Clonality
Monoclonal
Clone
PAT16E3AT
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
CLEC4E antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Form
Sterile Filtered clear solution.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Applications: CLEC4E antibody has been tested by ELISA, Western blot and Immunofluorescence analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis and Immunofluorescence is 1:250 ~ 500.Recommended starting dilution is 1:250
Host or Source
Mouse
Preservative
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Isotype
Mouse IgG2b heavy chain and κ light chain

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