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Beta-Catenin Antibody

CAT: 0013-GTR18206511Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18206511Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Goat polyclonal antibody to Catenin (cadherin-associated protein), beta 1. Beta Catenin is a 88 kDa protein and is a key downstream effector in the Wnt signalling pathway. It is involved in early embryonic development and tumorigenesis. Beta Catenin is part of a complex of proteins that constitute adherens junctions, necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. This protein anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.
Product Name Alternative
Cadherin-associated protein, CTNNB, CTNNB1, MRD19, armadillo antibody.
Reactivity
Canine, Human, Monkey, Mouse, Rat
Immunogen
Antigen: Purified recombinant peptide derived from within residues 731 aa to the C-terminus of human beta Catenin produced in E. coli. Antigen Sequence: MDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL
Target
Catenin (cadherin-associated protein), beta 1, 88kDa
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Epitope affinity purified
Concentration
Please inquire
Dilution
WB:1:500-1:2,000, IF:1:50-1:250, IHC-P:1:250-1:1,000
Form
Polyclonal antibody supplied as a 200 μl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The antibody solution should be gently mixed before use.
Tested Applications
IF, IHC-P, WB
Host or Source
Goat
Isotype
IgG

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