Triprolidine (hydrochloride monohydrate) (Standard)

Triprolidine (hydrochloride monohydrate) (Standard)

• CAS Number: 6138-79-0
• UNSPSC Description: Triprolidine (hydrochloride monohydrate) (Standard) is the analytical standard of Triprolidine (hydrochloride monohydrate). This product is intended for research and analytical applications. Triprolidine hydrochloride monohydrate, a first-generation antihistamine, is an oral active histamine H1 antagonist. Triprolidine hydrochloride monohydrate can be used for the research of allergic rhinitis. Triprolidine hydrochloride monohydrate exhibits spinal motor and sensory block in rats[1][2][3].
• Target Antigen: Histamine Receptor
• Type: Reference Standards
• Related Pathways: GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
• Field of Research: Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/triprolidine-hydrochloride-monohydrate-standard.html
• Smiles: CC1=CC=C(/C(C2=NC=CC=C2)=C\CN3CCCC3)C=C1.[H]Cl.[H]O[H]
• Molecular Weight: 332.87
• References & Citations: [1]K J Simons, et al. An investigation of the H1-receptor antagonist triprolidine: pharmacokinetics and antihistaminic effects. J Allergy Clin Immunol. 1986 Feb;77(2):326-30.|[2]D L Deal, et al. Disposition and metabolism of triprolidine in mice. Drug Metab Dispos. Nov-Dec 1992;20(6):920-7.|[3]Jann-Inn Tzeng, et al. Spinal sensory and motor blockade by intrathecal doxylamine and triprolidine in rats. J Pharm Pharmacol. 2018 Dec;70(12):1654-1661.
• Shipping Conditions: Room temperature