Products for Research Use Only

FBXW7 (C) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212196Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212196Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to FBXW7. F-box/WD repeat-containing protein 7 (FBXW7) is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXW7 probably recognizes and binds to phosphorylated target proteins. Furthermore, FBXW7 is involved in the degradation of cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
Product Name Alternative
Anti F-box/WD repeat-containing protein 7 antibody, anti Archipelago homolog antibody, anti hAgo antibody, anti F-box and WD-40 domaincontaining protein 7 antibody, anti F-box protein FBX30 antibody, anti SEL-10 antibody, anti hCdc4 antibody, anti FBW7 antibody, anti FBX30 antibody, anti SEL10 antibody
UniProt
Q969H0
Reactivity
Human
Immunogen
C-terminal region of human FBXW7
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
80
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human FBXW7.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3