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RAD18 (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212061Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212061Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to RAD18. E3 ubiquitin-protein ligase RAD18 belongs to the RAD18 family and is involved in postreplication repair of UV-damaged DNA. RAD18 associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on Lys-164. RAD18 also has ssDNA binding activity.
Product Name Alternative
Anti E3 ubiquitin-protein ligase RAD18 antibody, anti Postreplication repair protein RAD18 antibody, anti hHR18 antibody, anti hRAD18 antibody, anti RING finger protein 73 antibody, anti RNF73 antibody
UniProt
Q9NS91
Reactivity
Human, Mouse
Immunogen
N-terminal region of human RAD18
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
56
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human RAD18.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q9NS91

E3 ubiquitin-protein ligase RAD18

RAD18_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NS91
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RAD18
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.27
Processing
—
Secondary accessions
Q58F55, Q9NRT6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Cellular component

CytoplasmCytoskeletonNucleus

Biological process

DNA damageDNA repairUbl conjugation pathway

Molecular function

DNA-bindingTransferase

Ligand

Metal-bindingZinc

Domain

Zinc-finger

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