Recombinant Human RNAS2 Protein

• Background:

  This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. Eosinophil derived neurotoxin (EDN) is a protein belonging to the ribonuclease (RNase) A superfamily. It has recently been found to have antiviral activity against respiratory syncytial virus and human immunodeficiency virus in vitro.

• Abbreviation:

  RNAS2

• Synonyms:

  EDN; Non-secretory ribonuclease; RNS2

• UniProt:

  P10153

• Accession Number:

  P10153

• Expression System:

  HEK293 Cells

• Tag:

  C-His

• Sequence:

  Met 1-Ile161

• Field of Research:

  Epigenetics and Nuclear Signaling, Immunology

• Endotoxin:

  < 1.0 EU/mg of the protein as determined by the LAL method.

• Purity:

  > 85% as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  18.3 kDa

• Observed Molecular Weight:

  35.1 kDa

• Species:

  Human