HCV-IN-4

CAT: 0931-MF-0141315-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0141315-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2058080-25-2
Target
HCV Protease
Related Pathways
Microbiology/Virology|||Proteases/Proteasome
Bioactivity
HCV-IN-4, a potent and orally active inhibitor of HCV NS5A, demonstrates significant efficacy against genotypes GT1a, GT2b, GT3a, and the GT1a mutations Y93H and L31V. Its half-maximal effective concentrations (EC90s) are 3 pM, 0.3 nM, 0.01 nM, 0.5 nM, and 0.02 nM, respectively[1].
Smiles
FC1=C2C=3N([C@@H](OC2=CC(=C1)C=4NC(=NC4)[C@H]5N(C([C@@H](NC(OC)=O)C(C)C)=O)CCC5)C=6C=C7C(=CC6)CCCO7)C=8C(C3)=CC(=CC8)C=9NC(=NC9)[C@H]%10N(C([C@@H](NC(OC)=O)C(C)C)=O)CCC%10
Molecular Formula
C52H58FN9O8
Molecular Weight
956.07
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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