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Zopolrestat

CAT: 0804-HY-19687-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-19687-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Zopolrestat (CP73850) is a potent, orally active aldose reductase (AR) inhibitor with an IC50 of 3.1 nM. Zopolrestat is used for the research of diabetic complications[1].
CAS Number
110703-94-1
Product Name Alternative
CP73850
UNSPSC
12352005
Hazard Statement
H301, H413
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/zopolrestat.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)CC1=NN(CC2=NC3=CC(C(F)(F)F)=CC=C3S2)C(C4=C1C=CC=C4)=O
Molecular Formula
C19H12F3N3O3S
Molecular Weight
419.38
Precautions
H301, H413
References & Citations
[1]Mylari BL, et al. Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5- (trifluoromethyl) -2-benzothiazolyl] methyl]-1-phthalazineacetic acid (zopolrestat) and congeners. J Med Chem. 1991;34 (1) :108-122.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
BA7158-50Zopolrestat

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