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Zopolrestat

CAT: 0013-GTR19217101-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19217101-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Zopolrestat is a potent inhibitor of aldose reductase (IC50 = 3.1 nM) . (In Vitro) :Zopolrestat is a potent inhibitor of the enzymatic reduction of glyceraldehyde and glucose. (In Vivo) :After the administration of Zopolrestat (2.5 mg/kg-50 mg/kg; p.o), the ED50s in reversing already elevated sorbitol accumulation in rat sciatic nerve, retina, and lens in a chronic test were 1.9, 17.6, and 18.4 mg/kg, respectively.
CAS Number
110703-94-1
Product Name Alternative
CP 73850 | CP73850 | CP-73850 | Zopolrestat | Zopolrestatum
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (238.45 mM)
Smiles
OC (=O) Cc1nn (Cc2nc3cc (ccc3s2) C (F) (F) F) c (=O) c2ccccc12
Molecular Formula
C19H12F3N3O3S
Molecular Weight
419.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
BA7158-50Zopolrestat

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