5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone

5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone

• CAS Number: 1353676-65-9
• UNSPSC Description: 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone is a natural product that can be extracted from B. papyrifera. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone has potent anti-proliferation effects on ER-positive breast cancer cells, with an IC50 value of 4.41 μM for MCF-7 cells. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone also reduces the tumor growth in the BCAP-37 xenograft[1].
• Target Antigen: Others
• Type: Natural Products
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/5-7-3-4-tetrahydroxy-3-methoxy-8-5-diprenylflavone.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C(OC)=C(C2=CC(C/C=C(C)\C)=C(O)C(O)=C2)OC3=C(C/C=C(C)\C)C(O)=CC(O)=C13
• Molecular Weight: 452.50
• References & Citations: [1]FujiangGuo, et al. Prenylflavone derivatives from Broussonetia papyrifera, inhibit the growth of breast cancer cells in vitro and in vivo. Phytochemistry Letters. Volume 6, Issue 3, August 2013, Pages 331-336.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported