5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone

5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone

• CAS Number: 1268140-15-3
• UNSPSC Description: 5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone (compound 1), a flavonoid, is a potent ABCG2 inhibitor with an IC50 of 6.6 μM[1].
• Target Antigen: BCRP
• Type: Natural Products
• Related Pathways: Membrane Transporter/Ion Channel
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/5-7-3-trihydroxy-4-methoxy-8-prenylflavanone.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=C(O)C=C(O)C(C/C=C(C)\C)=C2O[C@H](C3=CC(O)=C(C=C3)OC)C1
• Molecular Weight: 370.40
• References & Citations: [1]Muhammad Ali Versiani, et al. Flavonoids from Eight Tropical Plant Species That Inhibit the Multidrug Resistance Transporter ABCG2. J Nat Prod. 2011 Feb 25;74(2):262-6.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported