SNCA Peptide

• NCBI Gene ID:

  6622

• Swiss Prot:

  P37840

• Accession Number:

  NP_000336

• Type:

  Peptides

• Concentration:

  200 ug/mL

• Buffer:

  PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store SNCA Peptide at -20˚ C, stable for one year.

• Applications Notes:

  The peptide is used for blocking the activity of SNCA Antibody (catalog number 7911) . It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37˚ C.

• NCBI Official Name:

  Synuclein, alpha (non A4 component of amyloid precursor)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ueda K, Fukushima H, Masliah E, et al. Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc. Natl. Acad. Sci. USA 1993; 90:11282-6.

• Background Reference 02:

  Pronin AN, Morris AJ, Surguchov A, et al. Synucleins are a novel class of substrates for G protein-coupled receptor kinases. J. Biol. Chem. 2000; 275:26515-22.

• Background Reference 03:

  Oaks AW, Frankfurt M, Finkelstein DI, et al. Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function. PLoS One 2013; 8:e60378.

• Background Reference 04:

  Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997; 276:2045-7.

• Other Product Names:

  PD1, NACP, PARK1, PARK4, Alpha-synuclein, Non-A beta component of AD amyloid

• Tested Applications:

  Blocking

• Species:

  Human

• Protein ID:

  6806898

• Physical Properties:

  Liquid