FLIP Peptide

• NCBI Gene ID:

  8837

• Swiss Prot:

  O15519

• Accession Number:

  AAC51622

• Type:

  Peptides

• Concentration:

  200 ug/mL

• Buffer:

  PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store FLIP peptide at -20˚ C, stable for one year.

• Applications Notes:

  FLIP peptide is used for blocking the activity of FLIP antibody.

• NCBI Official Name:

  CASP8 and FADD-like apoptosis regulator

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schroter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J. Inhibition of death receptor signals by cellular FLIP. Nature 1997;388:190-195.

• Background Reference 02:

  Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-89

• Background Reference 03:

  Hu Y, Benedict MA, Wu D, Inohara N, Nunez G. Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation. Proc Natl Acad Sci USA 1998;95:4386-91 (WD1299)

• Other Product Names:

  CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1, CASH, CASP8 and FADD-like apoptosis regulator, Caspase homolog

• Tested Applications:

  Blocking

• Species:

  Human

• Protein ID:

  2253679

• Physical Properties:

  Liquid