FLIP Peptide

• NCBI Gene ID:

  8837

• Swiss Prot:

  O15519

• Accession Number:

  AAC51622

• Type:

  Peptides

• Concentration:

  200 ug/mL

• Buffer:

  PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store FLIP peptide at -20˚ C, stable for one year.

• Applications Notes:

  FLIP peptide is used for blocking the activity of FLIP antibody.

• NCBI Official Name:

  CASP8 and FADD-like apoptosis regulator

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schroter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J. Inhibition of death receptor signals by cellular FLIP. Nature 1997;388:190-195.

• Background Reference 02:

  Zhang Y, Zhou L, Miller CA. A splicing variant of a death domain protein that is regulated by a mitogen-activated kinase is a substrate for c-Jun N-terminal kinase in the human central nervous system. Proc Natl Acad Sci U S A 1998;95:2586-2591

• Background Reference 03:

  Brown TL and Howe PH. MADD is highly homologous to a Rab3 guanine-nucleotide exchange protein (Rab3-GEP) . Curr Biol 1998;8:R191

• Other Product Names:

  CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1, CASH, CASP8 and FADD-like apoptosis regulator, Caspase homolog

• Tested Applications:

  Blocking

• Species:

  Human

• Protein ID:

  2253679

• Physical Properties:

  Liquid