KIF5C rabbit pAb

• Background:

  The protein encoded by this gene is a kinesin heavy chain subunit involved in the transport of cargo within the central nervous system. The encoded protein, which acts as a tetramer by associating with another heavy chain and two light chains, interacts with protein kinase CK2. Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations-2. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Jul 2015]

• Description:

  The protein encoded by this gene is a kinesin heavy chain subunit involved in the transport of cargo within the central nervous system. The encoded protein, which acts as a tetramer by associating with another heavy chain and two light chains, interacts with protein kinase CK2. Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations-2. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Jul 2015],

• Synonyms:

  Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2)

• Gene ID:

  3800

• UniProt:

  O60282

• Cellular Locus:

  Cytoplasm, cytoskeleton. Cell projection, dendrite. Abundant in distal regions of dendrites..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from human KIF5C AA range: 119-169

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB

• Validated Applications:

  WB

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000

• Molecular Weight:

  105kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  105 kD

• Subcellular Location:

  Cytoplasm, cytoskeleton . Cell projection, dendrite . Abundant in distal regions of dendrites. .

• Other Product Names:

  Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2)

• Gene ID (Human):

  3800

• SwissProt (Human):

  O60282