VEGF165 Recombinant Protein

• Background:

  VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.

• NCBI Gene ID:

  7422

• Swiss Prot:

  P15692-4

• Accession Number:

  NP_001028928.1

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Cell Cycle, Growth Factors, Obesity, Signal Transduction

• Purity:

  Greater than 98% by SDS-PAGE gel and HPLC analyses.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized VEGF165 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted VEGF165 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing VEGF165 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Vascular endothelial growth factor A

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  VPF, VEGF, MVCD1, Vascular endothelial growth factor A, Vascular permeability factor, VEGF-A

• Species:

  Human

• Protein ID:

  76781487

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3