Serpin A12 Recombinant Protein

• Background:

  Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three beta -sheets, nine alpha-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.

• NCBI Gene ID:

  145264

• Swiss Prot:

  Q8IW75

• Accession Number:

  Q8IW75

• Tag:

  N-GST tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Growth Factors, Immunology, Innate Immunity, Neuroscience, Obesity, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 50mM TrisHCl, 160mM NaCl, 0.2mM PMSF, 1mM DTT, 10% Glycerine, pH 7.2 . It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  71.4 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Serpin A12, OL-64, Visceral Adipose Tissue-Derived Serine Protease Inhibitor, Vaspin, Visceral Adipose-Specific Serpin, SERPINA12

• Species:

  Human

• Protein ID:

  929654682

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3