Uridine Phosphorylase 1 Recombinant Protein

• Background:

  Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase. UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The expression levels and the enzymatic activity of UPP1 are higher in human solid tumors than in adjacent normal tissues. The high level of UPP1 expression in some tumors makes it a potential prognosticfactor for some cancers, such as oral squamous cell carcinoma. UPP1 is important for the homeostatic regulation of intracellular and plasma uridine concentratios. UPP1 plays an important role in the pyrimidine salvage pathway through its catalysis of the reversible phosphorolysis of uridine to uracil.

• NCBI Gene ID:

  7378

• Swiss Prot:

  Q86Y75

• Accession Number:

  Q86Y75

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM Tris, 200mM NaCl, 1mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  21.3 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Uridine phosphorylase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  UPP1 Protein, Uridine Phosphorylase 1, UPP1

• Species:

  Human

• Protein ID:

  929654682

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3