Products for Research Use Only

TREM-1 Recombinant Protein

CAT: 0223-91-457Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-457Size:0.05 mg
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Background
Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) is a transmembrane protein with a single Ig-like domain. TREM-1 associates with the adapter protein, DAP12, to deliver an activating signal. TREM-1 is expressed on blood neutrophils and monocytes, and the expression is up-regulated by bacterial LPS. TREM-1 is expressed at high levels on neutrophils of patients with microbial sepsis and in mice with a TREM-1/Fc fusion protein protected mice against LPS-induced shock. Human TREM-1 shares 42% sequence homology with mouse TREM-1.
CAS Number
9000-83-3
NCBI Gene ID
54210
Swiss Prot
Q9NP99
Accession Number
Q9NP99
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Innate Immunity
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
21.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Triggering receptor expressed on myeloid cells 1
NCBI Organism
Homo sapiens
Other Product Names
Triggering Receptor Expressed on Myeloid Cells 1, TREM-1, Triggering Receptor Expressed on Monocytes 1, CD354, TREM1
Species
Human
Protein ID
78070603
Physical Properties
Lyophilized