TGF beta 3 Recombinant Protein

• Background:

  Transforming growth factor beta 3 (TGFB3) is a member of a TGF - beta superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- beta RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF- beta 3, mammals develop a deformity known as a cleft palate.

• NCBI Gene ID:

  7043

• Swiss Prot:

  P10600

• Accession Number:

  P10600

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Other

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 4 mM HCl. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  12.7 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Transforming growth factor beta 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Transforming growth factor beta-3, TGFB3, TGF-beta-3, Latency-associated peptide, LAP

• Species:

  Human, Mouse

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3