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Pro-NGF Recombinant Protein

CAT: 0223-91-064Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-064Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
CAS Number
9000-83-3
NCBI Gene ID
4803
Swiss Prot
P01138
Accession Number
P01138
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 250mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
25 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Nerve growth factor
NCBI Organism
Homo sapiens
Other Product Names
Beta-Nerve Growth Factor, Beta-NGF, NGF, NGFB
Species
Human
Physical Properties
Lyophilized

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