LTbetaR non-lytic Recombinant Protein

• Background:

  The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines, and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.

• NCBI Gene ID:

  4055

• Swiss Prot:

  P08164

• Accession Number:

  NP_002333

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  CHO cells

• Field of Research:

  Cancer, Cell Cycle, Chemokines & Cytokines, Immunology, Signal Transduction

• Buffer:

  Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μ g/ml in sterile PBS.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  Lymphotoxin beta receptor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Lymphotoxin-beta Receptor, Tumor Necrosis Factor Receptor 2 Related Protein, Tumor Necrosis Factor C Receptor, Tumor Necrosis Factor Receptor Superfamily Member 3, TNFRSF3

• Species:

  Human

• Protein ID:

  4505039

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3