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M-CSF Recombinant Protein

CAT: 0223-96-923Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-96-923Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. It is one of the three experimentally described colony-stimulating factors. M-CSF binds to the colony stimulating factor 1 receptor. Macrophage colony-stimulating factor has been shown to interact with PIK3R2. M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. Locally produced M-CSF in the vessel wall contributes to the development and progression of atherosclerosis.
CAS Number
9000-83-3
NCBI Gene ID
1435
Swiss Prot
P09603-1
Accession Number
P09603-1
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Chemokines & Cytokines, Growth Factors
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
26 kDa
Applications Notes
This recombinant protein can be used for E, WB. For research use only.
NCBI Official Name
Colony stimulating factor 1 (macrophage)
NCBI Organism
Homo sapiens
Background Reference 01
Sapi E., 2004, Exp. Biol. Med., 229 : 1-11.
Background Reference 02
Jang Mei-Huei, 2006, The Journal of Immunology, 177 (6) : 4055-4063.
Background Reference 03
Cao, Qi, 2014, Kidney International, 85 (4) : 794-806.
Other Product Names
M-CSF, CSF-1, Lanimostim
Tested Applications
ELISA, WB
Species
Human
Physical Properties
Lyophilized

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