M-CSF Recombinant Protein

• Background:

  The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. It is one of the three experimentally described colony-stimulating factors. M-CSF binds to the colony stimulating factor 1 receptor. Macrophage colony-stimulating factor has been shown to interact with PIK3R2. M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. Locally produced M-CSF in the vessel wall contributes to the development and progression of atherosclerosis.

• NCBI Gene ID:

  1435

• Swiss Prot:

  P09603-1

• Accession Number:

  P09603-1

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Chemokines & Cytokines, Growth Factors

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  26 kDa

• Applications Notes:

  This recombinant protein can be used for E, WB. For research use only.

• NCBI Official Name:

  Colony stimulating factor 1 (macrophage)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sapi E., 2004, Exp. Biol. Med., 229 : 1-11.

• Background Reference 02:

  Jang Mei-Huei, 2006, The Journal of Immunology, 177 (6) : 4055-4063.

• Background Reference 03:

  Cao, Qi, 2014, Kidney International, 85 (4) : 794-806.

• Other Product Names:

  M-CSF, CSF-1, Lanimostim

• Tested Applications:

  ELISA, WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3