TGF-beta receptor 2 Recombinant Protein

• Background:

  TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered through the TGF-beta receptor complex prompt various responses by the cell. One such response is to inhibit cell growth and division. Based on this action, the TGF-beta receptor type 2 is sometimes called a tumor suppressor. Defects in TGFBR2 have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome and the development of various types of tumors.

• NCBI Gene ID:

  7048

• Swiss Prot:

  P37173

• Accession Number:

  P37173

• Tag:

  C-Fc tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Signal Transduction

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  42.6 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Transforming growth factor beta receptor II

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TGF-beta receptor type-2, TGF-beta type II receptor, TGFBR2, Transforming growth factor-beta receptor type II

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3