CD8B Recombinant Protein

CAT: 0223-91-519Size: 0.05 mgDry Ice: NoHazardous: No
CAT#:0223-91-519Size:0.05 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
T-Cell Surface Glycoprotein CD8 beta Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
CAS Number
9000-83-3
NCBI Gene ID
926
Swiss Prot
P10966
Accession Number
P10966
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Immunology
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
17.8 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
CD8b molecule
NCBI Organism
Homo sapiens
Other Product Names
T-Cell Surface Glycoprotein CD8 Beta Chain, CD8b, CD8B1
Species
Human
Physical Properties
Lyophilized

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