CD3 epsilon Recombinant Protein

• Background:

  T-Cell Surface Glycoprotein CD3 epsilon Chain (CD3 epsilon) is a single-pass type I membrane protein. CD3 epsilon contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3 epsilon is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs) . TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

• NCBI Gene ID:

  916

• Swiss Prot:

  P07766

• Accession Number:

  P07766

• Tag:

  C-Fc tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Cancer, Immunology, Neuroscience, Signal Transduction, Stem Cell, Other

• Buffer:

  Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  38.7 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  CD3e molecule

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  T-Cell Surface Glycoprotein CD3 Epsilon Chain, T-Cell Surface Antigen T3/Leu-4 Epsilon Chain, CD3e, T3E

• Species:

  Human

• Protein ID:

  767983919

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3