Sorbitol Dehydrogenase Recombinant Protein

• Background:

  Sorbitol dehydrogenase, also known as L-iditol 2-dehydrogenase and SORD, is a member of the zinc-containing alcohol dehydrogenase family. SORD exsits in a homotetramer and binds one zinc ion per subunit. SORD is expressed in kidney and epithelial cells of both benign and malignant prostate tissue. SORD can converts sorbitol to fructose and catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase to make up the sorbitol pathway. SORD is up-regulated by androgens and down-regulated by castration. SORD may play a role in the sperm motility by providing an energetic source for sperm.

• NCBI Gene ID:

  6652

• Swiss Prot:

  Q00796

• Accession Number:

  Q00796

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl,0.2M NaCl,5mM DTT,20% glycerol, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  39.3 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Sorbitol dehydrogenase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Sorbitol Dehydrogenase, L-Iditol 2-Dehydrogenase, SORD

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3