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SLC1A5 Recombinant Protein

CAT: 0223-11-460Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-11-460Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sodium-dependent amino acids transporter (SLC1A5) that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904) .
CAS Number
9000-83-3
NCBI Gene ID
6510
Swiss Prot
Q15758
Accession Number
NP_005619.1
Tag
His Tag & TrxA Tag
Type
Recombinant Proteins
Source
E. coli
Purity
>90% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
22.5 kDa
Applications Notes
This protein carries a polyhistidine tag at the N-terminus, followed by a TrxA tag. The protein has a calculated MW of 22.5 kDa. The protein migrates as 24 KDa under reducing (R) condition (SDS-PAGE) .
NCBI Official Name
Solute carrier family 1 member 5
NCBI Organism
Homo sapiens
Background Reference 01
Kekuda R., et al. 1996, J Biol Chem., 271 (31), 18657-61.
Background Reference 02
Blond JL., et al. 2000, J Virol., 74 (7), 3321-9.
Background Reference 03
Sugimoto J., et al. 2017, Sci Rep., 3,1462.
Other Product Names
ASCT2, M7V1, RDR, RDRC, ATB (0), AAAT, ASCT2M7VS1, M7V1ATBO, R16, RD114, RDRCFLJ31068
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

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