SLC1A5 Recombinant Protein

• Background:

  Sodium-dependent amino acids transporter (SLC1A5) that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904) .

• NCBI Gene ID:

  6510

• Swiss Prot:

  Q15758

• Accession Number:

  NP_005619.1

• Tag:

  His Tag & TrxA Tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Purity:

  >90% as determined by SDS-PAGE.

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  22.5 kDa

• Applications Notes:

  This protein carries a polyhistidine tag at the N-terminus, followed by a TrxA tag. The protein has a calculated MW of 22.5 kDa. The protein migrates as 24 KDa under reducing (R) condition (SDS-PAGE) .

• NCBI Official Name:

  Solute carrier family 1 member 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kekuda R., et al. 1996, J Biol Chem., 271 (31), 18657-61.

• Background Reference 02:

  Blond JL., et al. 2000, J Virol., 74 (7), 3321-9.

• Background Reference 03:

  Sugimoto J., et al. 2017, Sci Rep., 3,1462.

• Other Product Names:

  ASCT2, M7V1, RDR, RDRC, ATB (0), AAAT, ASCT2M7VS1, M7V1ATBO, R16, RD114, RDRCFLJ31068

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3