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Serpin E2 Recombinant Protein

CAT: 0223-96-683Size: 0.025 mgDry Ice: NoHazardous: No
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CAT#:0223-96-683Size:0.025 mg
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Background
SERPINE2 is also known as Glia-derived nexin (GDN), Peptidase inhibitor 7 (PI7), Protease nexin 1 (PN1) . SERPINE2 is a secreted glycoprotein which belongs to the serpin family. SerpinE1 is the primary physiological inhibitor of the two plasminogen activators urokinase (uPA) and tissue plasminogen activator (tPA) . PAI-1 / GDN is also implicated in adipose tissue development. It suggests that PAI-1 inhibitors serve in the control of atherothrombosis. Defects in Serpin E1 / PN1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SerpinE1 defect in the plasma.
CAS Number
9000-83-3
NCBI Gene ID
5270
Swiss Prot
P07093
Accession Number
P07093-2
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cell Cycle, Neuroscience
Purity
>92% as determined by SDS-PAGE.
Buffer
20 mM NaAc, 100 mM NaCl, PH6.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
42.7 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
NCBI Organism
Homo sapiens
Background Reference 01
Gloor S.M., et al., 1986, Cell 47:687-693.
Background Reference 02
Scott R.W., et al., 1985, J. Biol. Chem. 260:7029-7034.
Other Product Names
SERPINE2, Glia-derived nexin, GDN, Peptidase inhibitor 7, PI-7, Protease nexin 1, PN-1, Serpin E2, SerpinE2, PI7
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

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