Repulsive guidance molecule A Recombinant Protein

• Background:

  Repulsive guidance molecule A (RGMA) is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1, BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.

• NCBI Gene ID:

  56963

• Swiss Prot:

  Q96B86

• Accession Number:

  Q96B86

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Neuroscience, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM Tris,150mM NaCl, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  29.8 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Repulsive guidance molecule family member a

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Repulsive guidance molecule A, RGM domain family member A, RGM, RGMA

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3