M-CSF Recombinant Protein

• Background:

  Rat Macrophage colony-stimulating factor 1 (MCSF, CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.

• NCBI Gene ID:

  78965

• Swiss Prot:

  Q8JZQ0

• Accession Number:

  Q8JZQ0

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Buffer:

  Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  25.2 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Colony stimulating factor 1

• NCBI Organism:

  Rattus norvegicus

• Other Product Names:

  Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, CSF1

• Species:

  Rat

• Protein ID:

  929654682

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3