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PDGF-BB Recombinant Protein

CAT: 0223-91-179Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-179Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
CAS Number
9000-83-3
NCBI Gene ID
5155
Swiss Prot
P01127
Accession Number
P01127
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Growth Factors, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 4mM HCl. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
12.42 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Platelet derived growth factor subunit B
NCBI Organism
Homo sapiens
Other Product Names
Platelet-Derived Growth Factor Subunit B, PDGF Subunit B, PDGF-2, Platelet-Derived Growth Factor B Chain, Platelet-Derived Growth Factor Beta Polypeptide, Proto-Oncogene c-Sis, Becaplermin, PDGFB, PDGF2, SIS
Species
Human
Physical Properties
Lyophilized

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