Peroxiredoxin-4 Recombinant Protein

• Background:

  Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.

• NCBI Gene ID:

  10549

• Swiss Prot:

  Q13162

• Accession Number:

  Q13162

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction, Other

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  33.8 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Peroxiredoxin 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Peroxiredoxin-4, Antioxidant Enzyme AOE372, AOE37-2, Peroxiredoxin IV, Prx-IV, Thioredoxin Peroxidase AO372, Thioredoxin-Dependent Peroxide Reductase A0372, PRDX4

• Species:

  Human

• Protein ID:

  767904139

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3