Products for Research Use Only
RegisterLogin

ULBP-1 Recombinant Protein

CAT: 0223-92-545Size: 0.05 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-92-545Size:0.05 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
NKG2D ligand 1, also called ULBP1, is a member of UL16-binding protein (ULBP) family which has also been termed the retinoic acid early transcript 1 (RAET1) family. Unlike the classical MHC class I molecules and the MIC molecules possess alpha1, alpha2 and alpha3 domains, ULBP/RAET1 family members lack alpha3 domain. ULBP1 is recognized by the activating receptor NKG2D on the surface of cytotoxic natural killer (NK) and T cells, and then promotes the lysis of cells expressing ULBP1 which is important for the immune surveillance. ULBP1 and several other family members, ULBP2 and ULBP5, own the ability to bind the human cytomegalovirus (CMV) UL16 glycoprotein. The human CMV glycoprotein UL16 binds to intracellular ULBP1 and so inhibits its expression at the cell surface, which reduces the susceptibility of the virus-infected cell to cytotoxic destruction by NK cells. The expression of ULBP1 has been found on some tumor cells and is implicated in tumor surveillance.
CAS Number
9000-83-3
NCBI Gene ID
80329
Swiss Prot
Q9BZM6
Accession Number
Q9BZM6
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
49.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
UL16 binding protein 1
NCBI Organism
Homo sapiens
Other Product Names
NKG2D ligand 1, NKG2DL1, ALCAN-beta, Retinoic acid early transcript 1I, UL16-binding protein 1, ULBP1, NKG2DL
Species
Human
Physical Properties
Lyophilized

Related Products

CatalogName
91-459ULBP-2 Recombinant Protein
91-915ULBP-2 Recombinant Protein
40-151-01PlGF-1 Recombinant Protein
40-576-01VAP-1 Recombinant Protein
40-390-01HCC-1 Recombinant Protein
40-362-01MCP-1 Recombinant Protein
40-324-01NNT-1 Recombinant Protein
40-290-01Cardiotrophin-1 Recombinant Protein
40-217-01WISP-1 Recombinant Protein
92-287Protachykinin-1 Recombinant Protein

Alternative Products

CatalogName
GTR18907452ULBP-1 Recombinant Protein
PROTQ9BZM6-20ugHuman ULBP-1 Recombinant Protein
NBP2-58022PEPULBP-1 Recombinant Protein Antigen
ATGP3479-250Recombinant human ULBP-1 protein
GTR19125076-01Recombinant Mouse ULBP-1 Protein
TMPY-01156-01ULBP-1 Protein, Human, Recombinant (His)
TMPJ-01212-01ULBP-1 Protein, Mouse, Recombinant (His)
GTR18910428ULBP-2 Recombinant Protein
TMPK-00134-01ULBP-1 Protein, Human, Recombinant (His & Avi)
TMPY-01405-01ULBP-1 Protein, Human, Recombinant (His & hFc)

Popular Products