Products for Research Use Only

HVEM Recombinant Protein

CAT: 0223-92-488Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-488Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mouse Protein Tnfrsf14, is a type I transmembrane protein belonging to the TNF receptor superfamily. It is tumor necrosis factor receptor superfamily member 14 and expressed on the surface of T cells during the resting state. Interaction of HVEM with TNF family member LIGHT co-stimulates T cells and promotes inflammation. HVEM also triggers inhibitory signaling cascade in effector T (Teff) cells and regulatory T cells (Tregs) as a ligand of B and T lymphocyte attenuator. Tnfrsf14 is detected in peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells. It has demonstrated that HVEM Ig is able to exert a significant antiviral effect against HSV-1 infection in vivo.
CAS Number
9000-83-3
NCBI Gene ID
230979
Swiss Prot
Q80WM9
Accession Number
Q80WM9
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
45.6 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
NCBI Organism
Mus musculus
Other Product Names
Protein Tnfrsf14, Herpesvirus entry mediator (HVEM), TR2 (TNF receptor-like molecule), ATAR (another TRAF-associated receptor), TNFRSF14, TR2, CD270
Species
Mouse
Protein ID
291219911
Physical Properties
Lyophilized