IFN gamma Recombinant Protein

• Background:

  Mouse Ifng is a secreted protein which belongs to the type I I (or gamma) interferon family. IFNG is produced by lymphocytes and activated by specific antigens or mitogens. In addition to having antiviral activity, IFNG also has important immunoregulatory functions. It is a potent activator of macrophages and has antiproliferative effects on transformed cells. It can potentiate the antiviral and antitumor effects of the type I interferons. Genetic variation in IFNG is associated with the risk of aplastic anemia (AA) which is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.

• NCBI Gene ID:

  15978

• Swiss Prot:

  P01580

• Accession Number:

  P01580

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Chemokines & Cytokines, Immunology, Innate Immunity

• Buffer:

  Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  15.5 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Interferon gamma

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Ifng, Interferon gamma, IFN-gamma

• Species:

  Mouse

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3