CD83 Recombinant Protein

• Background :

  Mouse CD83 is a 30-35kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells, neutrophils, monocytes and macrophages. Except for dendritic cells, CD83 expression is often transient. CD83 binds to sialic acids on target cells. Membrane CD83 promotes T cell proliferation, particularly of CD8+ cytotoxic T cells. Soluble CD83 is immunosuppressive and blocks T cell activation. On monocytes, CD83 is suggested to drive monocytes into a fibrocyte phenotype. A lack of membrane-expressed CD83 leads to an unusual IL-4/ IL-10 producing CD4+ T cell phenotype.

• NCBI Gene ID :

  12522

• Swiss Prot :

  P09920

• Accession Number :

  NP_033986

• Tag :

  Fc Tag

• Type :

  Recombinant Proteins

• Source :

  CHO cells

• Field of Research :

  Innate Immunity

• Buffer :

  Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μ g/ml in sterile PBS.

• Shipping Conditions :

  Room Temp

• Storage Conditions :

  Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.

• Applications Notes :

  This recombinant proteins is for research use only.

• NCBI Official Name :

  CD83 antigen

• NCBI Organism :

  Mus musculus

• Species :

  Mouse

• Protein ID :

  6753356

• Physical Properties :

  Lyophilized

• CAS Number :

  9000-83-3