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CD83 Recombinant Protein

CAT: 0223-90-404Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0223-90-404Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mouse CD83 is a 30-35kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells, neutrophils, monocytes and macrophages. Except for dendritic cells, CD83 expression is often transient. CD83 binds to sialic acids on target cells. Membrane CD83 promotes T cell proliferation, particularly of CD8+ cytotoxic T cells. Soluble CD83 is immunosuppressive and blocks T cell activation. On monocytes, CD83 is suggested to drive monocytes into a fibrocyte phenotype. A lack of membrane-expressed CD83 leads to an unusual IL-4/ IL-10 producing CD4+ T cell phenotype.
CAS Number
9000-83-3
NCBI Gene ID
12522
Swiss Prot
P09920
Accession Number
NP_033986
Tag
Fc Tag
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Innate Immunity
Buffer
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μ g/ml in sterile PBS.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
CD83 antigen
NCBI Organism
Mus musculus
Species
Mouse
Protein ID
6753356
Physical Properties
Lyophilized

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