CD83 Antibody [Michel17] (PE)

• Background:

  The Michel-17 monoclonal antibody specifically reacts with mouse CD83, a 45kDA type I transmembrane glycoprotein. CD83 is expressed mainly on activated lymphocytes and mature dendritic cells and it plays a role in T cell development. The Michel-17 antibody does not induce an activation signal on dendritic or T cells.

• NCBI Gene ID:

  12522

• Swiss Prot:

  O88324

• Host:

  Rat

• Reactivity:

  Mouse

• Clonality:

  Monoclonal

• Clone:

  Michel17

• Conjugation:

  PE

• Type:

  Primary Antibodies

• Field of Research:

  Innate Immunity

• Purification:

  The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

• Concentration:

  Batch dependent

• Buffer:

  Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

• Fragment:

  Rat IgG1

• Specificity:

  The Michel-17 monoclonal antibody specifically reacts with mouse CD83, a 45kDA type I transmembrane glycoprotein.

• Symbol:

  Cd83

• NCBI Official Name:

  CD83 antigen

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Cramer, S. O., Trumpfheller, C., Mehlhoop, U., Mor, S., Fleischer, B., von Bonin, A. (2000) . Activation-induced expression of murine CD83 on T cells and identification of a specific CD83 ligand on murine B cells.International immunology,12 (9), 1347-1351.

• Background Reference 02:

  Wolenski, M., Cramer, S. O., Ehrlich, S., Steeg, C., Fleischer, B., Von Bonin, A. (2003) . Enhanced Activation of CD83‐Positive T Cells*.Scandinavian journal of immunology,58 (3), 306-311.

• Background Reference 03:

  Breloer, M., Fleischer, B. (2008) . CD83 regulates lymphocyte maturation, activation and homeostasis.Trends in immunology,29 (4), 186-194.

• Other Product Names:

  Cd83, Cd83

• Tested Applications:

  Flow

• Physical Properties:

  Liquid