LILRB3 Recombinant Protein

• Background:

  Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3, ILT-5 or CD85a. LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.

• NCBI Gene ID:

  11025

• Swiss Prot:

  AAB68668 (P288R)

• Accession Number:

  AAB68668 (P288R)

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Immunology

• Buffer:

  Tris with Glycine, Arginine and NaCl, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  72.8 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  LILRB3 protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bashirova AA., et al., 2014, Immunogenetics.66:1-8.

• Background Reference 02:

  Huang J., et al., 2010, J Virol. 84 (18) :9463-9471. (3) Pfistershammer K., et al., 2009, Blood. 114 (11) :2323-2332.

• Other Product Names:

  LILRB3, CD85a, ILT5

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3