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LILRB2 Recombinant Protein

CAT: 0223-96-915Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-96-915Size:0.1 mg
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Background
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
CAS Number
9000-83-3
NCBI Gene ID
10288
Swiss Prot
Q8N423
Accession Number
AAH36827
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
74.4 kDa
Applications Notes
This recombinant protein can be used for E, WB. For research use only.
NCBI Official Name
Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
NCBI Organism
Homo sapiens
Background Reference 01
Borges L., et al., 1997, J. Immunol. 159:5192-5196.
Background Reference 02
Fanger N.A., et al., 1998, Eur. J. Immunol. 28:3423-3434.
Background Reference 03
Shiroishi M., et al., 2003, Proc. Natl. Acad. Sci. U.S.A. 100:8856-8861.
Other Product Names
LILRB2, ILT4, LIR2, MIR10, CD85d
Tested Applications
ELISA, WB
Species
Human
Physical Properties
Lyophilized

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