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LILRB2 Recombinant Protein

CAT: 0223-96-515Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-96-515Size:0.1 mg
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Background
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
CAS Number
9000-83-3
NCBI Gene ID
10288
Swiss Prot
Q8N423
Accession Number
AAH36827
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Purity
>92% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
48.6 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
NCBI Organism
Homo sapiens
Background Reference 01
Borges L., et al., 1997, J. Immunol. 159:5192-5196.
Background Reference 02
Fanger N.A., et al., 1998, Eur. J. Immunol. 28:3423-3434.
Background Reference 03
Shiroishi M., et al., 2003, Proc. Natl. Acad. Sci. U.S.A. 100:8856-8861.
Other Product Names
LILRB2, ILT4, LIR2, MIR10, CD85d
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

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