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IL-22 Recombinant Protein

CAT: 0223-92-663Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-663Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10R beta (previously known as CRF2-4), belonging to the class II cytokine receptor family.
CAS Number
9000-83-3
NCBI Gene ID
50929
Swiss Prot
Q9JJY9
Accession Number
Q9JJY9
Tag
C-mFc tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Chemokines & Cytokines, Immunology
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
43.8 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Interleukin 22
NCBI Organism
Mus musculus
Other Product Names
Interleukin-22, IL-22, IL-TIF alpha, IL-10-related T-cell-derived-inducible factor, IL-TIF, IL22, Interleukin-22a, IL-22a
Species
Mouse
Physical Properties
Lyophilized

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