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CD122 Recombinant Protein

CAT: 0223-96-463Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-96-463Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-2 receptor subunit beta (IL2RB) is also known as CD122, which Belongs to the type I cytokine receptor family. Type 4 subfamily. IL2RB contains 1 fibronectin type-III domain. IL2RB / CD122 is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2.
CAS Number
9000-83-3
NCBI Gene ID
3560
Swiss Prot
P14784
Accession Number
NP_000869.1
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Chemokines & Cytokines, Immunology, Other
Purity
>92% as determined by SDS-PAGE.
Buffer
50 mM tris, 100 mM glycine, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
50.7 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Interleukin 2 receptor, beta
NCBI Organism
Homo sapiens
Background Reference 01
Mulloy J.C., et al., 1996, J. Virol. 70:3599-3605.
Background Reference 02
Lindholm C.K., 2002, Biochem. Biophys. Res. Commun. 296:929-936.
Other Product Names
IL2RB, CD122, P70-75
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

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