IL-18 binding protein Recombinant Protein

• Background:

  Interleukin-18-binding protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mononuclear cells. IL18BP functions as an IL18 inhibitor. IL18BP binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. It has been shown that IL18BP may be a promising molecular approach to inhibit neointimal hyperplasia and arteriosclerosis progression following coronary and peripheral angioplasty.

• NCBI Gene ID:

  10068

• Swiss Prot:

  O95998

• Accession Number:

  O95998

• Tag:

  C-Fc tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Chemokines & Cytokines

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  44.7 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Interleukin 18 binding protein

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Interleukin-18-binding protein, Tadekinig-alfa and IL18BP, IL-18BP

• Species:

  Human

• Protein ID:

  530384410

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3